A novel controlled release drug delivery system for multiple drugs based on electrospun nanofibers containing nanoparticles. J Pharm Sci. 2010 May 3; Authors: Wang Y, Wang B, Qiao W, Yin T This study describes development of a novel controlled drug release system for multiple drugs, it consisted of Chitosan nanoparticles/PCL composite electrospun nanofibers with core-sheath structures. Two model agents' rhodamine B and naproxen were successfully loaded in the core and sheath region respectively. The behavior of these two agents demonstrated a good controlled release and temporality, providing a new way to obtain program or temporality release for multiple agents. Particularly, this is potential applications in the field of tissue engineering, sutures and wound dressings. (c) 2010 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci. PMID: 20821381 [PubMed - as supplied by publisher] |
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