Wednesday, November 10, 2010

[RegenMD] UNMC expands stem cell research

     
    RegenMD    
   
UNMC expands stem cell research
November 9, 2010 at 5:55 PM
 
On Tuesday, the med center announced creation of the Nebraska Regenerative Medicine Project and named UNMC stem cell researcher Nora Sarvetnick as its ...
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Hematopoietic Stem Cell Biology
November 9, 2010 at 4:00 PM
 
... stem cell transplantation, achieving better understanding of stem cell diseases such as leukemia and myeloma, and promoting regenerative medicine. ...
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UNMC expands stem cell work
November 9, 2010 at 4:00 PM
 
The project, announced Tuesday, will involve embryonic stem cells, adult stem cells and other forms of regenerative medicine. ...
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Kensey Nash and Arthrex Announce European Distribution Agreement for the ...
November 9, 2010 at 4:00 PM
 
"This partnership represents an important milestone as we continue Kensey Nash's mission as a developer of innovative regenerative medicine products," ...
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Effects of Nutrient Availability on Stem Cells
November 9, 2010 at 11:26 AM
 
... under stress is crucial for understanding their response to metabolic stress and wound healing as well as their role and use in regenerative medicine. ...
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Gallery: Military's freakiest medical projects
November 9, 2010 at 8:27 AM
 
With more troops surviving devastating injuries, the military is fast-tracking efforts in regenerative medicine, investigating risky measures to prevent ...
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Branched vascular network architecture: a new approach to lung assist device technology.
November 9, 2010 at 6:47 AM
 
Related Articles

Branched vascular network architecture: a new approach to lung assist device technology.

J Thorac Cardiovasc Surg. 2010 Nov;140(5):990-5

Authors: Hoganson DM, Anderson JL, Weinberg EF, Swart EJ, Orrick BK, Borenstein JT, Vacanti JP

OBJECTIVE: A lung assist device would serve an important clinical need as a bridge to transplant or destination therapy for patients with end-stage lung disease. A new lung assist device has been developed that incorporates a branched network of vascular channels adjacent to a gas chamber, separated by a thin, gas-permeable membrane. This study investigated 2 potential gas exchange membranes within this new architecture. METHODS: Oxygen and carbon dioxide exchange within the device was tested in vitro using 3 gas-permeable membranes. Two of the membranes, silicone only and silicone-coated microporous polymer, were plasma impermeable. The third, a microporous polymer, was used as a control. Gas exchange testing was done using anticoagulated porcine blood over a range of flow rates. RESULTS: Oxygen and carbon dioxide transfer was demonstrated in the device and increased nearly linearly from 0.6 to 8.0 mL/min blood flow for all of the membranes. There was no significant difference in the gas transfer between the silicone and the silicone-coated microporous polymer membranes. The transfer of oxygen and carbon dioxide in the device was similar to existing hollow fiber oxygenators controlling for surface area. CONCLUSIONS: The silicone and silicone-coated microporous polymer membranes both show promise as gas-permeable membranes in a new lung assist device design. Further optimization of the device by improving the membranes and reducing the channel diameter in the vascular network will improve gas transfer. The current device may be scaled up to function as an adult lung assist device.

PMID: 20591445 [PubMed - indexed for MEDLINE]

   
   
From miniature livers in the lab to human transplantation?
November 9, 2010 at 6:32 AM
 
... be used for human transplantation, researchers at the Wake Forest Institute for Regenerative Medicine have surpassed an early, but integral hurdle. ...
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Angioblast Systems wins grants under QTDP program
November 9, 2010 at 6:32 AM
 
Regenerative medicine company, Mesoblast Limited, has announced that its US associate company, Angioblast Systems, has secured $1.2 million in grants under ...
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