10/8 pubmed: adipose stem cell

Please add updates@feedmyinbox.com to your address book to make sure you receive these messages in the future. pubmed: adipose stem cell Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells. October 7, 2009 at 7:39 am Related Articles Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15720-5 Authors: Sun N, Panetta NJ, Gupta DM, Wilson KD, Lee A, Jia F, Hu S, Cherry AM, Robbins RC, Longaker MT, Wu JC Ectopic expression of transcription factors can reprogram somatic cells to a pluripotent state. However, most of the studies used skin fibroblasts as the starting population for reprogramming, which usually take weeks for expansion from a single biopsy. We show here that induced pluripotent stem (iPS) cells can be generated from adult human adipose stem cells (hASCs) freshly isolated from patients. Furthermore, iPS cells can be readily derived from adult hASCs in a feeder-free condition, thereby eliminating potential variability caused by using feeder cells. hASCs can be safely and readily isolated from adult humans in large quantities without extended time for expansion, are easy to maintain in culture, and therefore represent an ideal autologous source of cells for generating individual-specific iPS cells. PMID: 19805220 [PubMed - in process] Mesenchymal stromal cell and mononuclear cell therapy in heart disease. October 7, 2009 at 7:39 am Mesenchymal stromal cell and mononuclear cell therapy in heart disease. Future Cardiol. 2008 Sep;4(5):481-94 Authors: Haack-Sorensen M, Friis T, Kastrup J Despite progress in percutaneous coronary intervention, bypass surgery and drug therapy, rates of mortality and morbidity after acute coronary syndrome are high due to ventricular remodeling and heart failure. Mesenchymal stromal cells (MSCs) from adult bone marrow or adipose tissue are considered potential candidates for therapeutic regenerative treatment in cardiovascular disease. Recent animal studies have demonstrated that MSCs can induce neovascularization and improve myocardial function in postinfarction myocardial ischemic hearts. This review will focus on the present preclinical and clinical knowledge about the use of mononuclear cells and MSCs for cardiac regenerative medicine, the source of MSCs for clinical use and problems to consider when conducting clinical MSC therapy. PMID: 19804342 [PubMed - in process] Cardiac regenerative potential of adipose tissue-derived stem cells. October 7, 2009 at 7:39 am Related Articles Cardiac regenerative potential of adipose tissue-derived stem cells. Acta Physiol Hung. 2009 Sep;96(3):251-65 Authors: Hoke NN, Salloum FN, Loesser-Casey KE, Kukreja RC Myocyte loss due to ischemia/reperfusion injury leads to cardiac dysfunction and heart failure, and the concentration of current therapy is limited on preventing the progression. Recent interest has focused on transplantation of stem cells to differentiate and replenish the loss of myocytes. Adipose tissue represents an alternative and abundant source of adult stem cells with the ability to differentiate along multiple lineage pathways. Recent studies have demonstrated the potential of adipose tissue-derived stem cells for treatment of acute myocardial infarction. The aim of this review is to discuss the potential therapeutic benefits of adipose tissue-derived stem cells in improving cardiac function post-injury. PMID: 19706369 [PubMed - indexed for MEDLINE]   This email was sent to agupta1213+termsc@gmail.com.  Manage Your Account Don't want to receive this feed any longer? Unsubscribe here.