3/19 RegenMD

Please add updates@feedmyinbox.com to your address book to make sure you receive these messages in the future. RegenMD A hierarchical response of cells to perpendicular micro- and nanometric textural cues. March 18, 2010 at 8:10 AM Related Articles A hierarchical response of cells to perpendicular micro- and nanometric textural cues. IEEE Trans Nanobioscience. 2009 Sep;8(3):219-25 Authors: Seunarine K, Curtis AS, Meredith DO, Wilkinson CD, Riehle MO, Gadegaard N In this paper, we report on the influence of shallow micro- and nanopatterned substrata on the attachment and behavior of a human fibroblast [human telomerase transfected immortalized (hTERT)] cells. We identify a h! ierarchy of textural guidance cues with respect to cell alignment on these substrates. Cells were seeded and cultured for 48 h on silicon substrates patterned with two linear textures overlaid at 90 degrees, both with 24 microm pitch: a micrograting and a nanopattern of rows of 140- nm-diameter pits arranged in a rectangular array with 300 nm centre-to-centre spacing. The cell response to these textures was shown to be highly dependent on textural feature dimensions. We show that cells align to the stripes of nanopits. Stripes of 30-nm deep nanopits were also shown to elicit a stronger response from cells than 160-nm deep nanopits. PMID: 19278933 [PubMed - indexed for MEDLINE]   Capitol Newspaper Explores CIRM Accountability Issues March 18, 2010 at 4:32 AM   Reading List on CIRM Conflicts of Interest March 18, 2010 at 4:31 AM   This email was sent to regenmd@gmail.com.  Account Login Don't want to receive this feed any longer? Unsubscribe here This email was carefully delivered by Feed My Inbox. 230 Franklin Road Suite 814 Franklin, TN 37064