10/29 RegenMD

RegenMD         Alameda news briefs October 28, 2010 at 6:25 PM   BioTime focuses on regenerative medicine and blood plasma volume expanders. It also develops and markets research products in the field of stem cells and ... See all stories on this topic »         Plants Don't Transport Nanoparticles Within Their Tissue October 28, 2010 at 4:32 PM   Awards: Tissue engineering and structural composite research projects earn top honors. Metal Toxicity: The metal leads to oxidative stress in cells and, ... See all stories on this topic » Chemical & Engineering News         Researchers generate iPSCs to further treatments for lung disease October 28, 2010 at 11:03 AM   (Boston) A team of researchers from Boston University's Center for Regenerative Medicine and the Pulmonary Center have generated 100 new lines of human ... See all stories on this topic »         The Cheap Approach: Manipulating Polymer Nanofibers with Inexpensive Salts October 28, 2010 at 10:51 AM   These properties make them widely applicable in various areas such as membrane fabrication, tissue engineering, biomedical devices, or optical sensors. ... See all stories on this topic »         Legal Decision Keeps Competitors in the Game in KCI's Key Niche October 28, 2010 at 9:28 AM   Beyond VAC, the firm's regenerative medicine business remains on track to meet our expectations while the therapeutic surfaces business continues to ... See all stories on this topic »         Hey2 acts upstream of Notch in hematopoietic stem cell specification in zebrafish embryos. October 28, 2010 at 8:57 AM   Related Articles Hey2 acts upstream of Notch in hematopoietic stem cell specification in zebrafish embryos. Blood. 2010 Sep 23;116(12):2046-56 Authors: Rowlinson JM, Gering M Hematopoietic stem cells (HSCs) are essential for homeostasis and injury-induced regeneration of the vertebrate blood system. Although HSC transplantations constitute the most common type of stem cell therapy applied in the clinic, we know relatively little about the molecular programming of HSCs during vertebrate embryogenesis. In vertebrate embryos, HSCs form in close association with the ventral wall of the dorsal aorta. We have shown previously that in zebrafish, HSC formation depends on the presence of a signaling cascade that involves Hedgehog, vascular endothelial growth factor, and Notch signaling. Here, we reveal that Hey2, a hairy/enhancer-of-split-related basic helix-loop-helix transcription factor often believed to act downstream of Notch, is also required for HSC formation. In dorsal aorta progenitors, Hey2 expression is induced downstream of cloche and the transcription factor Scl/Tal1, and is maintained by Hedgehog and vascular endothelial growth factor signaling. Whereas knockdown of Hey2 expression results in a loss of Notch receptor expression in dorsal aorta angioblasts, activation of Notch signaling in hey2 morphants rescues HSC formation in zebrafish embryos. These results establish an essential role for Hey2 upstream of Notch in HSC formation. PMID: 20511544 [PubMed - indexed for MEDLINE]         Stanford University opens new stem cell building, bucking federal restrictions October 28, 2010 at 5:51 AM   "The stem cell revolution has been launched in California," Bob Klein of the California Institute for Regenerative Medicine declared at the afternoon ... See all stories on this topic »         What's the future of Stem Cells? Boobies! October 28, 2010 at 2:12 AM   Recently, Sharon Begley of Wired Magazine reported in her article, "All Natural: Why Breasts Are the Key to the Future of Regenerative Medicine," that it is ... See all stories on this topic »         City of Hope awarded $6.3 million in grants October 28, 2010 at 2:12 AM   DUARTE - City of Hope researchers have been awarded $6.3 million by the California Institute for Regenerative Medicine (CIRM) for research and development ... See all stories on this topic »         The IP Picture for iPS Cells October 28, 2010 at 2:12 AM   By Tobias Brambrink and Maryanne Trevisan October 28, 2010 | Expert Commentary | The regenerative medicine field has seen an intense effort in recent years ... See all stories on this topic »             This email was sent to regenmd@gmail.com. Delivered by Feed My Inbox 230 Franklin Road Suite 814 Franklin, TN 37064 Account Login Unsubscribe Here