Tuesday, February 15, 2011

2/16 RegenMD

     
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Hospital backs project to repair damaged hearts
February 15, 2011 at 7:49 PM
 
THE Great Western Hospital has been raising awareness of the British Heart Foundation's (BHF) new Mending Broken Hearts Appeal – a new research project looking into using regenerative medicine to repair damaged hearts of patients. ...
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Meat-lovers get food for thought in futuristic US lab
February 15, 2011 at 7:42 PM
 
About 10 years ago, Mironov's research dream to grow "cultured meat" became reality when he was awarded a grant from the National Aeronautics and Space Administration (NASA) for cardiovascular tissue engineering. He landed the grant with the help of ...
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Sardar Patel University to host Indo-Australian meet
February 15, 2011 at 7:42 PM
 
VADODARA/ANAND: Sardar Patel University (SPU) in Vallabh Vidyanagar will for the first time host Indo-Australian conference on biomaterials, tissue engineering and drug delivery systems. During the three-day conference, the Society for Biomaterials and ...
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BioTime Buys Assets from Cell Targeting to Boost Its Regenerative Medicine Focus
February 15, 2011 at 6:41 PM
 
... a core of stem cell and related manufacturing technologies capable of enabling our development of a wide array of therapeutic products in the emerging field of regenerative medicine," remarks Michael D. West, Ph.D., president and CEO of BioTime.
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BioTime Announces Agreement To Acquire Glycosan BioSystems
February 15, 2011 at 6:41 PM
 
Glycosan's products have the demonstrated ability to support the growth and directed differentiation of stem cells and are designed as implantable, resorbable matrices for tissue engineering, regenerative medicine, and for research applications ...
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Seeing local scientists at heart of regenerative medicine
February 15, 2011 at 6:41 PM
 
Tonight, in "How to Build a Beating Heart,'' National Geographic Explorer investigates those efforts to transform human health, revealing the pulse-quickeningly cool side of regenerative medicine. The cast includes a slate of local scientists with ...
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Boston Globe
   
   
2011 Veterinary Regenerative Medicine Conference to be Held in Kentucky
February 15, 2011 at 11:37 AM
 
The North American Veterinary Regenerative Medicine Association (NAVRMA) announced Feb. 7 that online registration is open for the 2nd annual North American ...
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Meat-lovers get food for thought in futuristic US lab
February 15, 2011 at 9:45 AM
 
... meat" became reality when he was awarded a grant from the National Aeronautics and Space Administration (NASA) for cardiovascular tissue engineering. ...
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BioTime signs deal to purchase Glycosan BioSystems assets; and Cell Targeting
February 15, 2011 at 7:00 AM
 
US biotech BioTime (NYSE Amex: BTX), a company that develops and markets products in the field of stem cells and regenerative medicine, says it has signed a ...
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IL-2-controlled expression of multiple T cell trafficking genes and Th2 cytokines in the regulatory T cell-deficient scurfy mice: implication to multiorgan inflammation and control of skin and lung inflammation.
February 15, 2011 at 6:49 AM
 

IL-2-controlled expression of multiple T cell trafficking genes and Th2 cytokines in the regulatory T cell-deficient scurfy mice: implication to multiorgan inflammation and control of skin and lung inflammation.

J Immunol. 2011 Jan 15;186(2):1268-78

Authors: Sharma R, Sharma PR, Kim YC, Leitinger N, Lee JK, Fu SM, Ju ST

Scurfy (Sf) mice bear a mutation in the Foxp3 transcription factor, lack regulatory T cells (Treg), develop multiorgan inflammation, and die prematurely. The major target organs affected are skin, lungs, and liver. Sf mice lacking the Il2 gene (Sf.Il2(-/-)), despite being devoid of Treg, did not develop skin and lung inflammation, but the inflammation in liver, pancreas, submandibular gland, and colon remained. Genome-wide microarray analysis revealed hundreds of genes that were differentially regulated among Sf, Sf.Il2(-/-), and B6 CD4(+) T cells, but the most significant changes were those encoding receptors for trafficking/chemotaxis/retention and cytokines. Our study suggests that IL-2 controls the skin and lung inflammation in Sf mice in an apparent "organ-specific" manner through two novel mechanisms: by regulating the expression of genes encoding a variety of receptors for T cell trafficking/chemotaxis/retention and by regulating Th2 cell expansion and cytokine production. Thus, IL-2 is potentially a master regulator for multiorgan inflammation and an underlying etiological factor for various diseases associated with skin and lung inflammation.

PMID: 21169543 [PubMed - indexed for MEDLINE]

   
   
Public, Researchers, Industry Left in Dark on CIRM Chair Selection Criteria
February 15, 2011 at 2:29 AM
 
   
     
 
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