Wednesday, February 3, 2010

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A novel jet-based nano-hydroxyapatite patterning technique for osteoblast guidance.
February 3, 2010 at 5:58 PM

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A novel jet-based nano-hydroxyapatite patterning technique for osteoblast guidance.

J R Soc Interface. 2010 Jan 6;7(42):189-97

Authors: Li X, Koller G, Huang J, Di Silvio L, Renton T, Esat M, Bonfield W, Edirisinghe M

Surface topography is well known to play a crucial role in influencing cellular responses to an implant material and is therefore important in bo! ne tissue regeneration. A novel jet-based patterning technique, template-assisted electrohydrodynamic atomization spraying, was recently devised to control precisely the surface structure as well as its dimensions. In the present study, a detailed investigation of this patterning process was carried out. A range of nano-hydroxyapatite (nHA) line-shaped patterns <20 microm in width were successfully deposited on a commercially pure Ti surface by controlling the flow of an nHA suspension in an electric field. In vitro studies showed that the nHA patterns generated are capable of regulating the human osteoblast cell attachment and orientation.

PMID: 19493897 [PubMed - indexed for MEDLINE]

 

Public Can Participate Today in CIRM Board Meeting at Locations in San Francisco, San Diego and Los Angeles
February 3, 2010 at 6:17 AM

 

Scathing Commentary on CIRM from San Diego Union-Tribune
February 3, 2010 at 5:37 AM

 

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