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Please add updates@feedmyinbox.com to your address book to make sure you receive these messages in the future. RegenMD Progenitor Cells for Regenerative Medicine and Consequences of ART and Cloning-Associated Epimutations. February 19, 2010 at 2:16 PM Related Articles Progenitor Cells for Regenerative Medicine and Consequences of ART and Cloning-Associated Epimutations. Mol Biotechnol. 2010 Feb 17; Authors: Laprise SL The "holy grail" of regenerative medicine is the identification of an undifferentiated progenitor cell that is pluripotent, patient specific, and ethically unambiguous. Such a progenitor cell must also be able to differentiate into functional, transplantable tissue! , while avoiding the risks of immune rejection. With reports detailing aberrant genomic imprinting associated with assisted reproductive technologies (ART) and reproductive cloning, the idea that human embryonic stem cells (hESCs) derived from surplus in vitro fertilized embryos or nuclear transfer ESCs (ntESCs) harvested from cloned embryos may harbor dangerous epigenetic errors has gained attention. Various progenitor cell sources have been proposed for human therapy, from hESCs to ntESCs, and from adult stem cells to induced pluripotent stem cells (iPS and piPS cells). This review highlights the advantages and disadvantages of each of these technologies, with particular emphasis on epigenetic stability. PMID: 20162468 [PubMed - as supplied by publisher]   CIRM Trio Says Alquist Legislation Creates Unnecessary Jeopardy February 18, 2010 at 5:48 PM   This email was sent to regenmd@gmail.com.  Account Login Don't want to receive this feed any longer? Unsubscribe here This email was carefully delivered by Feed My Inbox. 230 Franklin Road Suite 814 Franklin, TN 37064