2/4 TE-RegenMed-StemCell feed

Please add updates@feedmyinbox.com to your address book to make sure you receive these messages in the future. TE-RegenMed-StemCell feed Cord blood-derived CD133+ cells improve cardiac function after myocardial infarction February 3, 2010 at 4:47 PM   Stanford researchers explore link between human birth defect syndrome, cancer metastasis February 3, 2010 at 2:47 PM   Scientists map epigenome of human stem cells during development February 3, 2010 at 2:47 PM   Public Can Participate Today in CIRM Board Meeting at Locations in San Francisco, San Diego and Los Angeles February 3, 2010 at 2:17 PM Biotech executives, researchers and the public can participate in today's meeting of the board of directors of the California stem cell agency at locations in San Francisco, Los Angeles and San Diego.It may be the first time that three such widespread locations have been available around the state for a CIRM board meeting. The sites are the Hotel Whitcomb in San Francisco(where the meeting is   Scathing Commentary on CIRM from San Diego Union-Tribune February 3, 2010 at 1:37 PM The San Diego Union-Tribune today blistered the California stem cell agency in an editorial calling for greater transparency and a "much less blithe attitude about conflicts of interest."The editorial carried the headline: "Stem-cell shenanigans / Lawmakers should force state institute to shape up." The San Diego paper said,"This reeks. It increasingly appears as if the Legislature needs to save   GEN Feb. 1 issue features special focus on epigenetics February 3, 2010 at 12:46 PM   A novel jet-based nano-hydroxyapatite patterning technique for osteoblast guidance. February 3, 2010 at 6:53 AM Related Articles A novel jet-based nano-hydroxyapatite patterning technique for osteoblast guidance. J R Soc Interface. 2010 Jan 6;7(42):189-97 Authors: Li X, Koller G, Huang J, Di Silvio L, Renton T, Esat M, Bonfield W, Edirisinghe M Surface topography is well known to play a crucial role in influencing cellular responses to an implant material and is therefore important in bone tissue regeneration. A novel jet-based patterning technique, template-assisted electrohydrodynamic atomization spraying, was recently devised to control precisely the surface structure as well as its dimensions. In the present study, a detailed investigation of this patterning process was carried out. A range of nano-hydroxyapatite (nHA) line-shaped patterns <20 microm in width were successfully deposited on a commercially pure Ti surface by controlling the flow of an nHA suspension in an electric field. In vitro studies showed that the nHA patterns generated are capable of regulating the human osteoblast cell attachment and orientation. PMID: 19493897 [PubMed - indexed for MEDLINE]   Use of adipose stem cells and polylactide discs for tissue engineering of the temporomandibular joint disc. February 3, 2010 at 6:30 AM Related Articles Use of adipose stem cells and polylactide discs for tissue engineering of the temporomandibular joint disc. J R Soc Interface. 2010 Jan 6;7(42):177-88 Authors: Mäenpää K, Ellä V, Mauno J, Kellomäki M, Suuronen R, Ylikomi T, Miettinen S There is currently no suitable replacement for damaged temporomandibular joint (TMJ) discs after discectomy. In the present study, we fabricated bilayer biodegradable polylactide (PLA) discs comprising a non-woven mat of poly(L/D)lactide (P(L/D)LA) 96/4 and a P(L/DL)LA 70/30 membrane plate. The PLA disc was examined in combination with adipose stem cells (ASCs) for tissue engineering of the fibrocartilaginous TMJ disc in vitro. ASCs were cultured in parallel in control and chondrogenic medium for a maximum of six weeks. Relative expression of the genes, aggrecan, type I collagen and type II collagen present in the TMJ disc extracellular matrix increased in the ASC-seeded PLA discs in the chondrogenic medium. The hypertrophic marker, type X collagen, was moderately induced. Alcian blue staining showed accumulation of sulphated glycosaminoglycans. ASC differentiation in the PLA discs was close to that observed in pellet cultures. Comparison of the mRNA levels reveal! ed that the degree of ASC differentiation was lower than that in TMJ disc-derived cells and tissue. The pellet format supported the phenotype of the TMJ disc-derived cells under chondrogenic conditions and also enhanced their hyalinization potential, which is considered part of the TMJ disc degeneration process. Accordingly, the combination of ASCs and PLA discs has potential for the development of a tissue-engineered TMJ disc replacement. PMID: 19474082 [PubMed - indexed for MEDLINE]   This email was sent to regenmd@gmail.com.  Manage Your Account Don't want to receive this feed any longer? Unsubscribe here.