9/30 pubmed: adipose stem cell

Please add updates@feedmyinbox.com to your address book to make sure you receive these messages in the future. pubmed: adipose stem cell Responses of adipose-derived stem cells during hypoxia: enhanced skin-regenerative potential. September 29, 2009 at 8:30 am Related Articles Responses of adipose-derived stem cells during hypoxia: enhanced skin-regenerative potential. Expert Opin Biol Ther. 2009 Sep 28; Authors: Chung HM, Won CH, Sung JH Mesenchymal stem cells within the stromal-vascular fraction of subcutaneous adipose tissue (i.e., adipose-derived stem cells (ASCs)), have been used for tissue engineering. In addition to serving a building-block function, ASCs are reported to secrete growth factors that are essential for their function. Increasing evidence indicates that ASCs play a significant role in skin regeneration, a function that is enhanced by hypoxia through upregulating secretion of growth factors. Although the anatomical sites of ASCs in the body are relatively oxygen-deficient, ASCs are usually cultured under normoxic conditions (i.e., atmospheric oxygen levels). Culturing ASCs under physiologically relevant low-oxygen-tension conditions may uniquely benefit the expansion, differentiation, adhesion, growth factor secretion and regenerative potential of ASCs. Therefore, understanding the response and adaptation of ASCs to hypoxia may be invaluable for developing novel cell- and cyto-therapy strategies. This review highlights our current understanding of cellular and molecular responses of ASCs to hypoxia, focusing on the enhancement of ASC function and secretory activity by hypoxic culture conditions. PMID: 19780713 [PubMed - as supplied by publisher] Hemangioblastic characteristics of human adipose tissue-derived adult stem cells in vivo. September 29, 2009 at 8:30 am Related Articles Hemangioblastic characteristics of human adipose tissue-derived adult stem cells in vivo. Arch Med Res. 2009 May;40(4):311-7 Authors: Fang B, Luo S, Song Y, Li N, Cao Y Recent studies have demonstrated the existence of a population of adipose tissue-derived adult stem (ADAS) cells that can undergo multilineage differentiation in vitro. However, it remains unclear whether these cells maintain their multilineage potential in vivo. The aim of this study was to investigate whether Flk1(+)CD31(-)CD34(-) ADAS cells have characteristics of hemangioblasts. These human ADAS (hADAS) cells were able to differentiate into endothelial and hematopoietic cells at the single-cell level in vivo. These postnatal Flk1(+)CD31(-)CD34(-) hADAS cells bear characteristics of hemangioblast and may have potential application for the hematopoietic and vascular diseases. PMID: 19608022 [PubMed - indexed for MEDLINE]   This email was sent to agupta1213+termsc@gmail.com.  Manage Your Account Don't want to receive this feed any longer? Unsubscribe here.