9/5 pubmed: "regenerative medici...

Please add updates@feedmyinbox.com to your address book to make sure you receive these messages in the future. pubmed: "regenerative medici... Hybrid structure in PCL-HAp scaffold resulting from biomimetic apatite growth. September 4, 2009 at 7:25 am Related Articles Hybrid structure in PCL-HAp scaffold resulting from biomimetic apatite growth. J Mater Sci Mater Med. 2009 Aug 29; Authors: Lebourg M, Antón JS, Ribelles JL Polymer-ceramic composites are favourite candidates when aiming to replace bone tissue. We present here scaffolds made of polycaprolactone-hydroxyapatite (PCL-HAp) composites, and investigate in vitro mineralisation of the scaffolds in SBF after or without a nucleation treatment. In vitro bioactivity is enhanced by HAp incorporation as well as by nucleation treatment, as demonstrated by simulated body fluid (SBF) mineralization. Surprisingly, we obtained a hybrid interconnected organic-inorganic structure, as a result of micropore invasion by biomimetic apatite, which results in a mechanical strengthening of the material after two weeks of immersion in SBFx2. The presented scaffolds, due to their multiple qualities, are expected to be valuable supports for bone tissue engineering. PMID: 19728046 [PubMed - as supplied by publisher] ES, iPS, MSC, and AFS cells. Stem cells exploitation for Pediatric Surgery: current research and perspective. September 4, 2009 at 7:25 am Related Articles ES, iPS, MSC, and AFS cells. Stem cells exploitation for Pediatric Surgery: current research and perspective. Pediatr Surg Int. 2009 Sep 1; Authors: Pozzobon M, Ghionzoli M, De Coppi P Despite the advancements that have been made in treating infants with congenital malformations, these still represent a major cause of disease and death during the first years of life and childhood. Regeneration of natural tissue from living cells to restore damaged tissues and organs is the main purpose of regenerative medicine. This relatively new field has emerged by the combination of tissue engineering and stem cell transplantation as a possible strategy for the replacement of damaged organs or tissues. This review would like to offer an insight on the latest evolution of stem cells with a glance at their possible application for regenerative medicine, particularly in the Paediatric Surgery field. PMID: 19727766 [PubMed - as supplied by publisher] In vitro Proliferation and Osteogenic Differentiation of Human Bone Marrow-derived Mesenchymal Stem Cells Cultured with Hardystonite (Ca2ZnSi2O7) and {beta}-TCP Ceramics. September 4, 2009 at 7:25 am Related Articles In vitro Proliferation and Osteogenic Differentiation of Human Bone Marrow-derived Mesenchymal Stem Cells Cultured with Hardystonite (Ca2ZnSi2O7) and {beta}-TCP Ceramics. J Biomater Appl. 2009 Sep 2; Authors: Lu H, Kawazoe N, Tateishi T, Chen G, Jin X, Chang J The effects of hardystonite (Ca2ZnSi2O7, CSZn) and tricalcium phosphate (beta-TCP) on the proliferation and osteogenic differentiation of human bone marrow-derived mesenchymal stem cells (MSCs) were compared by directly culturing MSCs on ceramic disks (contact mode) or separately culturing cells with ceramic disks (non-contact mode). In non-contact mode, the CSZn ceramic supported MSC proliferation more strongly than did the beta-TCP ceramic. However, in contact mode, the MSCs proliferated more quickly on the beta-TCP ceramic than they did on the CSZn ceramic. Alkaline phosphatase (ALP) staining and osteogenic gene expression analysis showed that the CSZn and beta-TCP ceramics had significant effects on the promotion of the osteogenic differentiation of MSCs in both non-contact and contact mode. Furthermore, in contact mode, the CSZn disk promoted the osteogenic differentiation of MSCs more strongly than did the beta-TCP disks. Even without the induction of dexamethasone and beta-glycerophosphate, CSZn stimulated the osteogenic differentiation of MSCs. These results suggest that CSZn ceramic would be a useful candidate material for bone regeneration and hard tissue engineering. PMID: 19726532 [PubMed - as supplied by publisher] [Biocompatibility of polylactic-co-glycolic acid for culturing bFGF gene-transfected bone marrow stromal cells and application of the cell complex for repairing rabbit cartilage defect.] September 4, 2009 at 7:25 am Related Articles [Biocompatibility of polylactic-co-glycolic acid for culturing bFGF gene-transfected bone marrow stromal cells and application of the cell complex for repairing rabbit cartilage defect.] Nan Fang Yi Ke Da Xue Xue Bao. 2009 Jun;29(6):1123-6 Authors: Cao B, Xu ZS, Xiao DM, Lin BW, Lu XH, Li R OBJECTIVE: To evaluate the biocompatibility of polylactic-co-glycolic acid (PLGA) for culturing bFGF gene-transfected bone marrow stromal cells (BMSCs) and assess the feasibility of this cell complex for repairing cartilage defect in rabbits using tissue engineering method. METHODS: BMSCs transfected by bFGF gene were cultured on PLGA matrix to assess the biocompatibility of PLGA. The cell complex was then implanted into the cartilage defect in rabbits, and its effect in cartilage defect repair was evaluated by histological observation and immunohistochemical staining. RESULTS: BMSCs transfected by bFGF gene grew normally on PLGA matrix. After implantation, the complex showed good effect for cartilage defect repair in rabbits. CONCLUSION: PLGA has good biocompatibility with the transfected BMSCs, and the cell complex can be used for repairing rabbit cartilage defect and may potentially serve as a substitute of cartilage autograft. PMID: 19726338 [PubMed - in process] [Possibility of iPS cells (discussion)] September 4, 2009 at 7:25 am Related Articles [Possibility of iPS cells (discussion)] Brain Nerve. 2009 Jun;61(6):711-8 Authors: Okano H, Yamanaka S, Tsuji S PMID: 19658270 [PubMed - indexed for MEDLINE] [Cell transplantation and regenerative therapy for neurological disorders--special reference to cerebral ischemia] September 4, 2009 at 7:25 am Related Articles [Cell transplantation and regenerative therapy for neurological disorders--special reference to cerebral ischemia] No To Hattatsu. 2009 May;41(3):197-202 Authors: Yasuhara T, Date I PMID: 19517790 [PubMed - indexed for MEDLINE] [Neurosurgical approaches to pediatric neurological disorders. Introduction] September 4, 2009 at 7:25 am Related Articles [Neurosurgical approaches to pediatric neurological disorders. Introduction] No To Hattatsu. 2009 May;41(3):172-4 Authors: Date H, Oi S PMID: 19517785 [PubMed - indexed for MEDLINE]   This email was sent to agupta1213+termsc@gmail.com.  Manage Your Account Don't want to receive this feed any longer? Unsubscribe here.